We are applying the latest approaches in genome sequencing and proteomics for applications in aquaculture, including to characterize and diagnose disease agents and better understand their evolution, to monitor immune responses, and to establish associations between genomic variation and commercially-important trait variation.
Houston RD, Macqueen DJ. 2018. Atlantic salmon (Salmo salar L.) genetics in the 21st century: taking leaps forward in aquaculture and biological understanding. Animal Genet. In Press,
Gallagher MD, Matejusova I, Nguyen L, Ruane NM, Falk N, Macqueen DJ. 2018. Nanopore sequencing for rapid diagnostics of salmonid RNA viruses. Sci. Rep. 8: 16307. DOI: 10.1038/s41598-018-34464-x
Macqueen DJ, Primmer CR, Houston RD, Nowak BF, Bernatchez L, Bergseth S, Davidson WS, Gallardo-Escárate C, Goldammer T, Guiguen Y, Iturra P, Kijas JW, Koop BF, Lien S, Maass A, Martin SAM, McGinnity P, Montecino M, Naish KA, Nichols KM, Ólafsson K, Omholt SW, Palti Y, Plastow GS, Rexroad CE, Rise MR, Ritchie RJ, Sandve SR, Schulte PM, Tello A, Vidal R, Vik JO, Wargelius A, Yáñez JM (The FAASG Consortium. Functional Annotation of All Salmonid Genomes (FAASG): an international initiative supporting future salmonid research, conservation and aquaculture. BMC Genomics, In Press.
Bruno DW, Noguera PA, Black J, Murray W, Macqueen DJ, Matejusova I. 2014. Identification of a wild reservoir of salmonid alphavirus in common dab Limanda limanda with emphasis on virus culture and sequencing. Aquacult. Environ. Interac. 5: 89-98. DOI: 10.3354/aei00097
Oxford Nanopore minION sequencer used in Macqueen lab for whole viral genome sequencing