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Fish health and physiology

The group has long-standing interests in fish physiology and health, with a current focus on immune function and long term interests in growth and muscle development. We are characterising these systems at the molecular and cellular level, with a focus on understanding regulation of gene expression. We are currently focusing on leveraging single cell omics to resolve the cell-specific basis for fish health traits.

Representative papers:

Daniels RR, Taylor RT, Robledo D, Macqueen DJ. 2023. Single cell genomics as a transformative approach for aquaculture research and innovation. Reviews in Aquaculture. https://doi.org/10.1111/raq.12806

 

Taylor RT,  Daniels RR,  Dobie R, Naseer S, Clark T, Henderson N,  Boudinot P,  Martin SA, Macqueen DJ. 2022. Single cell transcriptomics of Atlantic salmon (Salmo salar L.) liver reveals cellular heterogeneity and immunological responses to challenge by Aeromonas salmonicida. Front. Immunol. doi: 10.3389/fimmu.2022.984799

 

Bakke FK, Monte M, Stead DA, Cornulier T, Causey DR, Douglas A, Macqueen DJ*, Dooley H*. 2020. Plasma proteome responses in salmonid fish following immunization. Front. Immunol. doi: 10.3389/fimmu.2020.581070 * Joint corresponding and senior author 

 
Fig. 1.png
From Sun et al. 2024. Cell atlas of the Atlantic salmon spleen reveals immune cell heterogeneity and cell-specific responses to bacterial infection. Fish Shellfish Immunol. 109358. doi: 10.1016/j.fsi.2024.109358. 
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