Fish health and physiology
The group has long-standing interests in fish physiology and health, with a focus on systems that regulate growth and immunity. We are characterising these systems at the molecular and cellular level, with a focus on understanding regulation of gene expression. We are currently using single cell genomics to resolve the cell-specific basis for fish health traits.
Bakke FK, Monte M, Stead DA, Cornulier T, Causey DR, Douglas A, Macqueen DJ*, Dooley H*. 2020. Plasma proteome responses in salmonid fish following immunization. Front. Immunol. doi: 10.3389/fimmu.2020.581070 * Joint corresponding and senior author
Kim J-H, Macqueen DJ, Winton JR, Hansen JD, Park H, Devlin RH. 2019. Effect of growth rate on transcriptomic responses to immune stimulation in wild-type, domesticated, and GH-transgenic coho salmon. BMC Genomics. 20: 1024.
Causey DR, Kim JH, Devlin RH, Martin SAM, Macqueen DJ. 2019. The AMPK system of salmonid fishes was expanded through genome duplication and is regulated by growth and immune status in muscle. Sci. Rep. 9: 9819
Causey DR, Potz M, Stead DA, Secombes CJ, Macqueen DJ. 2018. High-throughput proteomic expression profiling of the fish liver response to bacterial challenge. BMC Genomics. 19: 719
Causey DR, Kim JH, Stead DA, Devlin RH, Martin SAM, Macqueen DJ. 2018. Proteomic comparison of selective breeding and growth hormone transgenesis in fish: Unique pathways to enhanced growth J. Proteomics. pii: S1874-3919(18)30325-7.
From Causey et al. 2018. High-throughput proteomic expression profiling of the fish liver response to bacterial challenge. BMC Genomics. 19: 719.