Fish health and physiology
The group has long-standing interests in fish physiology and health, with a focus on systems that regulate growth and immunity. We are characterising these systems at the molecular and cellular level, with a focus on understanding regulation of gene expression. We are currently using single cell genomics to resolve the cell-specific basis for fish health traits.
Taylor RT, Daniels RR, Dobie R, Naseer S, Clark T, Henderson N, Boudinot P, Martin SA, Macqueen DJ. 2022. Single cell transcriptomics of Atlantic salmon (Salmo salar L.) liver reveals cellular heterogeneity and immunological responses to challenge by Aeromonas salmonicida. Front. Immunol. doi: 10.3389/fimmu.2022.984799
Bakke FK, Monte M, Stead DA, Cornulier T, Causey DR, Douglas A, Macqueen DJ*, Dooley H*. 2020. Plasma proteome responses in salmonid fish following immunization. Front. Immunol. doi: 10.3389/fimmu.2020.581070 * Joint corresponding and senior author