Fish health and physiology

The group has long-standing interests in fish physiology and health, with a focus on systems that regulate growth and immunity. We are characterising these systems at the molecular and cellular level, with a focus on understanding regulation of gene expression. 

Representative papers:
Kim J-H, Macqueen DJ, Winton JR, Hansen JD, Park H, Devlin RH. 2019. Effect of growth rate on transcriptomic responses to immune stimulation in wild-type, domesticated, and GH-transgenic coho salmon. BMC Genomics. 20: 1024.
Causey DR, Kim JH, Devlin RH, Martin SAM, Macqueen DJ. 2019. The AMPK system of salmonid fishes was expanded through genome duplication and is regulated by growth and immune status in muscle. Sci. Rep. 9: 9819
 
Causey DR, Potz M, Stead DA, Secombes CJ, Macqueen DJ. 2018. High-throughput proteomic expression profiling of the fish liver response to bacterial challenge. BMC Genomics. 19: 719

Causey DR, Kim JH, Stead DA, Devlin RH, Martin SAM, Macqueen DJ. 2018. Proteomic comparison of selective breeding and growth hormone transgenesis in fish: Unique pathways to enhanced growth J. Proteomics. pii: S1874-3919(18)30325-7.
 
Alzaid A, Kim J-H, Devlin RH, Martin SAM, Macqueen DJ. 2018. Growth hormone transgenesis in coho salmon disrupts muscle immune function impacting cross-talk with growth systems. J. Exp. Biol. In Press. 
 
From Causey et al. 2018. High-throughput proteomic expression profiling of the fish liver response to bacterial challenge. BMC Genomics. 19: 719.