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Fish health and physiology

The group has long-standing interests in fish physiology and health, with a focus on systems that regulate growth and immunity. We are characterising these systems at the molecular and cellular level, with a focus on understanding regulation of gene expression. We are currently using single cell genomics to resolve the cell-specific basis for fish health traits.

Representative papers:

Daniels RR, Taylor RT, Robledo D, Macqueen DJ. 2023. Single cell genomics as a transformative approach for aquaculture research and innovation. Reviews in Aquaculture. https://doi.org/10.1111/raq.12806

 

Taylor RT,  Daniels RR,  Dobie R, Naseer S, Clark T, Henderson N,  Boudinot P,  Martin SA, Macqueen DJ. 2022. Single cell transcriptomics of Atlantic salmon (Salmo salar L.) liver reveals cellular heterogeneity and immunological responses to challenge by Aeromonas salmonicida. Front. Immunol. doi: 10.3389/fimmu.2022.984799

 

Bakke FK, Monte M, Stead DA, Cornulier T, Causey DR, Douglas A, Macqueen DJ*, Dooley H*. 2020. Plasma proteome responses in salmonid fish following immunization. Front. Immunol. doi: 10.3389/fimmu.2020.581070 * Joint corresponding and senior author 

 
Fig. 1.png
From Causey et al. 2018. High-throughput proteomic expression profiling of the fish liver response to bacterial challenge. BMC Genomics. 19: 719.
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